{"id":46,"date":"2024-10-25T20:15:13","date_gmt":"2024-10-25T20:15:13","guid":{"rendered":"https:\/\/hightidetx.com\/?page_id=46"},"modified":"2025-09-23T11:57:31","modified_gmt":"2025-09-23T03:57:31","slug":"discovery-portfolio","status":"publish","type":"page","link":"https:\/\/www.hightidetx.com\/cn\/science\/discovery-portfolio\/","title":{"rendered":"\u65e9\u7814\u7ba1\u7ebf"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">\u541b\u5723\u6cf0\u7684\u65e9\u671f\u7814\u53d1\u5e03\u5c40\u4f53\u73b0\u4e86\u6211\u4eec\u81f4\u529b\u4e8e\u63a8\u52a8\u53d8\u9769\uff0c\u4ee5\u653b\u514b\u6162\u6027\u4ee3\u8c22\u75be\u75c5\u548c\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u51b3\u5fc3\u3002<\/h2>\n\n\n\n<p>\u9664\u4e86\u5df2\u5904\u4e8e\u4e34\u5e8a\u9636\u6bb5\u7684\u5019\u9009\u836f\u7269\uff0c\u6211\u4eec\u7684\u79d1\u5b66\u5bb6\u4eec\u6b63\u5728\u7814\u53d1\u4f5c\u4e3a\u201c\u5e73\u8861\u4ee3\u8c22\u8c03\u8282\u5242\u201d\u7684\u521b\u65b0\u7597\u6cd5\uff0c\u65e8\u5728\u6062\u590d\u7ebf\u7c92\u4f53\u5065\u5eb7\u6240\u9700\u7684\u9002\u5f53\u5e73\u8861\uff0c\u5e76\u6ee1\u8db3\u80a5\u80d6\u75c7\u3001\u76f8\u5173\u5fc3\u810f\u4ee3\u8c22\u75be\u75c5\u4e0e\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u60a3\u8005\u7684\u672a\u5c3d\u4e4b\u9700\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full hide\"><img loading=\"lazy\" decoding=\"async\" width=\"936\" height=\"414\" src=\"https:\/\/hightidetx.com\/wp-content\/uploads\/2024\/11\/pipeline-image.png\" alt=\"\" class=\"wp-image-574\" srcset=\"https:\/\/www.hightidetx.com\/cn\/wp-content\/uploads\/sites\/2\/2024\/11\/pipeline-image.png 936w, https:\/\/www.hightidetx.com\/cn\/wp-content\/uploads\/sites\/2\/2024\/11\/pipeline-image-300x133.png 300w, https:\/\/www.hightidetx.com\/cn\/wp-content\/uploads\/sites\/2\/2024\/11\/pipeline-image-768x340.png 768w\" sizes=\"auto, (max-width: 936px) 100vw, 936px\" \/><\/figure>\n\n\n<table id='pipe-2' class=\"pipeline_cont pipeline-desk\"><tbody><tr><th class='myth column-1'><\/th><th class='myth column-2'>\u5019\u9009\u5316\u5408\u7269<\/th><th class='myth column-3'>\u836f\u7269\u53d1\u73b0<\/th><th class='myth column-4'>\u975eGLP\u6bd2\u7406<\/th><th class='myth column-5'>IND\u652f\u6301<\/th><th class='myth column-6'>\u4e34\u5e8a1\u671f<\/th><\/tr><tr class='drugtitlerow'><td colspan=2><h4 class='has-black-color'>\u9152\u7cbe\u6027\u809d\u708e<\/h4><\/td><td><\/td><td><\/td><td><\/td><td><\/td><\/tr><tr id='tr-0'>\n<td class='drug_detailsX'><div class=\"nolink\">&nbsp;<\/div><\/td><td class='indication'>HTD4010<\/td><td class='drug_progress'><div class='dh current' data-width='99'><p><\/p><\/div><\/td><td><\/td><td><\/td><td><\/td><\/tr><tr id='tr-0-b' class='description'><td colspan=5><div class='closeme_cont'><div class='closeme'><div class='arrowlink'><i class='fa-solid fa-arrow-up'><\/i><\/div> Read Less<\/div><\/div><td><\/tr><tr class='drugtitlerow'><td colspan=2><h4 class='has-black-color'>\u51cf\u91cd\uff08\u4f53\u91cd\u4f18\u8d28\u8c03\u8282\uff09<\/h4><\/td><td><\/td><td><\/td><td><\/td><td><\/td><\/tr><tr id='tr-0'>\n<td class='drug_detailsX'><div class=\"nolink\">&nbsp;<\/div><\/td><td class='indication'>HTF1037 (\u7ebf\u7c92\u4f53\u89e3\u5076\u8054\u5242)<\/td><td class='drug_progress'><div class='dh current' data-width='53'><p><\/p><\/div><\/td><td><\/td><td><\/td><td><\/td><\/tr><tr id='tr-0-b' class='description'><td colspan=5><div class='closeme_cont'><div class='closeme'><div class='arrowlink'><i class='fa-solid fa-arrow-up'><\/i><\/div> Read Less<\/div><\/div><td><\/tr><tr id='tr-1'>\n<td class='drug_detailsX'><div class=\"nolink\">&nbsp;<\/div><\/td><td class='indication'>\u7ebf\u7c92\u4f53\u89e3\u5076\u8054\u52a0\u5176\u4ed6\u673a\u5236<br>(\u591a\u4e2a\u521b\u65b0\u6027\u5316\u5408\u7269)<\/td><td class='drug_progress'><div class='dh current' data-width='13'><p><\/p><\/div><\/td><td><\/td><td><\/td><td><\/td><\/tr><tr id='tr-1-b' class='description'><td colspan=5><div class='closeme_cont'><div class='closeme'><div class='arrowlink'><i class='fa-solid fa-arrow-up'><\/i><\/div> Read Less<\/div><\/div><td><\/tr><tr class='drugtitlerow'><td colspan=2><h4 class='has-black-color'>\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5<\/h4><\/td><td><\/td><td><\/td><td><\/td><td><\/td><\/tr><tr id='tr-0'>\n<td class='drug_detailsX'><div class=\"nolink\">&nbsp;<\/div><\/td><td class='indication'>HTF1057 (\u7ebf\u7c92\u4f53\u89e3\u5076\u8054\u5242)<\/td><td class='drug_progress'><div class='dh current' data-width='48'><p><\/p><\/div><\/td><td><\/td><td><\/td><td><\/td><\/tr><tr id='tr-0-b' class='description'><td colspan=5><div class='closeme_cont'><div class='closeme'><div class='arrowlink'><i class='fa-solid fa-arrow-up'><\/i><\/div> Read Less<\/div><\/div><td><\/tr><tr id='tr-1'>\n<td class='drug_detailsX'><div class=\"nolink\">&nbsp;<\/div><\/td><td class='indication'>\u7ebf\u7c92\u4f53\u89e3\u5076\u8054\u52a0\u5176\u4ed6\u673a\u5236<br>\uff08\u65b0\u578b\u5316\u5408\u836f\u7269\uff09<\/td><td class='drug_progress'><div class='dh current' data-width='15'><p><\/p><\/div><\/td><td><\/td><td><\/td><td><\/td><\/tr><tr id='tr-1-b' class='description'><td colspan=5><div class='closeme_cont'><div class='closeme'><div class='arrowlink'><i class='fa-solid fa-arrow-up'><\/i><\/div> Read Less<\/div><\/div><td><\/tr><\/tbody><\/table><div class='legendX'><\/div><table class=\"pipeline_cont pipeline-mobile\"><tbody><tr><th>Therapeutic Area<\/th><th><\/th><th>Phase<\/th><\/tr><tr id='mobiletr-0'>\n<td class='drug_detailsX'><span class='has-black-color'>\u9152\u7cbe\u6027\u809d\u708e<\/span><\/td>\n<td class='drug_detailsY'>HTD4010<\/td><td class='stage'>\u4e34\u5e8a1\u671f<p class='small'><\/p><\/td><\/tr><tr id='mobtr-0-b' class='description'><td colspan=0><div class='closeme_cont'><div class='closeme'><div class='arrowlink'><i class='fa-solid fa-arrow-up'><\/i><\/div> Read Less<\/div><\/div><\/tr><tr><th>Therapeutic Area<\/th><th><\/th><th>Phase<\/th><\/tr><tr id='mobiletr-0'>\n<td class='drug_detailsX'><span class='has-black-color'>\u51cf\u91cd\uff08\u4f53\u91cd\u4f18\u8d28\u8c03\u8282\uff09<\/span><\/td>\n<td class='drug_detailsY'>HTF1037 (\u7ebf\u7c92\u4f53\u89e3\u5076\u8054\u5242)<\/td><td class='stage'>IND\u652f\u6301<p class='small'><\/p><\/td><\/tr><tr id='mobtr-0-b' class='description'><td colspan=0><div class='closeme_cont'><div class='closeme'><div class='arrowlink'><i class='fa-solid fa-arrow-up'><\/i><\/div> Read Less<\/div><\/div><\/tr><tr id='mobiletr-1'>\n<td class='drug_detailsX'><span class='has-black-color'>\u51cf\u91cd\uff08\u4f53\u91cd\u4f18\u8d28\u8c03\u8282\uff09<\/span><\/td>\n<td class='drug_detailsY'>\u7ebf\u7c92\u4f53\u89e3\u5076\u8054\u52a0\u5176\u4ed6\u673a\u5236<br>(\u591a\u4e2a\u521b\u65b0\u6027\u5316\u5408\u7269)<\/td><td class='stage'>\u836f\u7269\u53d1\u73b0<p class='small'><\/p><\/td><\/tr><tr id='mobtr-1-b' class='description'><td colspan=0><div class='closeme_cont'><div class='closeme'><div class='arrowlink'><i class='fa-solid fa-arrow-up'><\/i><\/div> Read Less<\/div><\/div><\/tr><tr><th>Therapeutic Area<\/th><th><\/th><th>Phase<\/th><\/tr><tr id='mobiletr-0'>\n<td class='drug_detailsX'><span class='has-black-color'>\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5<\/span><\/td>\n<td class='drug_detailsY'>HTF1057 (\u7ebf\u7c92\u4f53\u89e3\u5076\u8054\u5242)<\/td><td class='stage'>\u975eGLP\u6bd2\u7406<p class='small'><\/p><\/td><\/tr><tr id='mobtr-0-b' class='description'><td colspan=0><div class='closeme_cont'><div class='closeme'><div class='arrowlink'><i class='fa-solid fa-arrow-up'><\/i><\/div> Read Less<\/div><\/div><\/tr><tr id='mobiletr-1'>\n<td class='drug_detailsX'><span class='has-black-color'>\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5<\/span><\/td>\n<td class='drug_detailsY'>\u7ebf\u7c92\u4f53\u89e3\u5076\u8054\u52a0\u5176\u4ed6\u673a\u5236<br>\uff08\u65b0\u578b\u5316\u5408\u836f\u7269\uff09<\/td><td class='stage'>\u836f\u7269\u53d1\u73b0<p class='small'><\/p><\/td><\/tr><tr id='mobtr-1-b' class='description'><td colspan=0><div class='closeme_cont'><div class='closeme'><div class='arrowlink'><i class='fa-solid fa-arrow-up'><\/i><\/div> Read Less<\/div><\/div><\/tr><\/tbody><\/table>\n\n\n\n<p class=\"references\">\u66f4\u65b0\u65f6\u95f4:2024\u5e7410\u6708<\/p>\n\n\n\n<p><\/p>\n\n\n<ul class='tablist'><li class='activetab tablink' data-tab-index='0'><h5>\u9152\u7cbe\u6027\u809d\u708e<\/h5><\/li><li class='tablink' data-tab-index='1'><h5>\u4f53\u91cd\u4f18\u8d28\u8c03\u8282<\/h5><\/li><li class='tablink' data-tab-index='2'><h5>\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5<\/h5><\/li><\/ul><\/div><!-- entry-content --><\/article><\/div><!-- site-content --><\/div><!-- safezone a --><div style=\"background-color:#e5f1fa;\" class=\"fw_cont\"><div class=\"safezoneA\"><div class=\"entry-content\">\n\n\n<div class='activetabsection tabcont' id=tabcont-1>\n\n\n\n<p>HTD4010\u662f\u4e00\u4e2a\u5904\u4e8e\u4e34\u5e8a\u9636\u6bb5\u7684\u5728\u7814\u836f\u7269\uff0c\u65e8\u5728\u6cbb\u7597\u5305\u62ec\u9152\u7cbe\u6027\u809d\u708e\u5728\u5185\u7684\u6025\u6027\u708e\u75c7\u76f8\u5173\u75be\u75c5\u3002\u8be5\u5316\u5408\u7269\u662f\u4e00\u79cdReg3\u03b1\u86cb\u767d\u884d\u751f\u80bd\uff0c\u5177\u6709\u514d\u75ab\u8c03\u8282\u3001\u6297\u708e\u548c\u6297\u51cb\u4ea1\u4f5c\u7528\u3002HTD4010\u5728\u6025\u6027\u80f0\u817a\u708e\u548c\u6025\u6027\u809d\u8870\u7aed\u7684\u52a8\u7269\u6a21\u578b\u4e2d\u8868\u73b0\u51fa\u663e\u8457\u7684\u4fdd\u62a4\u4f5c\u7528\u3002<\/p>\n\n\n<\/div>\n\n\n<div class='tabcont' id=tabcont-2>\n\n\n\n<p>\u51cf\u91cd\u5e26\u6765\u7684\u5065\u5eb7\u76ca\u5904\u5df2\u88ab\u5e7f\u6cdb\u8ba4\u53ef\u3002\u5bf9\u4e8e\u80a5\u80d6\u60a3\u8005\u800c\u8a00\uff0c\u51cf\u91cd\u53ef\u6709\u6548\u6539\u5584\u7cd6\u5c3f\u75c5\u3001\u51a0\u5fc3\u75c5\u53ca\u4e0e\u80a5\u80d6\u76f8\u5173\u7684\u5176\u4ed6\u4ee3\u8c22\u6027\u98ce\u9669\u56e0\u7d20\u3002\u7136\u800c\uff0c\u6291\u5236\u98df\u6b32\u6240\u5e26\u6765\u7684\u51cf\u91cd\uff0c\u53ef\u80fd\u5bfc\u81f4\u808c\u8089\u6d41\u5931\uff1b\u8fd9\u53ef\u80fd\u4f1a\u524a\u5f31\u51cf\u91cd\u5e26\u6765\u7684\u5065\u5eb7\u83b7\u76ca\uff0c\u5e76\u53ef\u80fd\u589e\u52a0\u808c\u5c11\u75c7\u7684\u98ce\u9669\uff0c\u5bfc\u81f4\u884c\u52a8\u80fd\u529b\u4e0b\u964d\u3001\u8eab\u4f53\u6108\u53d1\u865a\u5f31\uff0c\u8fdb\u800c\u4f7f\u6574\u4f53\u751f\u6d3b\u8d28\u91cf\u964d\u4f4e\u3002<br><br>\u901a\u8fc7\u6fc0\u6d3b\u7ebf\u7c92\u4f53\u89e3\u5076\u8054\u673a\u5236\uff0c\u4e0d\u4ec5\u6709\u671b\u5b9e\u73b0\u51cf\u8102\u4fdd\u808c\u7684\u51cf\u91cd\u6548\u679c\uff0c\u8fd8\u80fd\u901a\u8fc7\u589e\u52a0I\u578b\u808c\u7ea4\u7ef4\uff08\u6709\u6c27\u4ee3\u8c22\uff09\u7684\u6bd4\u4f8b\u589e\u5f3a\u673a\u4f53\u8010\u529b\uff0c\u51cf\u5c11\u809d\u810f\u7b49\u5185\u810f\u8102\u80aa\uff0c\u6539\u5584\u8840\u7cd6\u63a7\u5236\uff0c\u5e76\u6709\u6548\u964d\u4f4e\u6c27\u5316\u5e94\u6fc0\u548c\u708e\u75c7\u6c34\u5e73\u3002<\/p>\n\n\n<\/div>\n\n\n<div class='tabcont' id=tabcont-3>\n\n\n\n<p>\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u662f\u73b0\u4ee3\u533b\u5b66\u9762\u4e34\u7684\u6700\u5177\u6311\u6218\u6027\u7684\u6cbb\u7597\u96be\u9898\u4e4b\u4e00\u3002\u5c3d\u7ba1\u5df2\u6709\u6570\u5341\u5e74\u7684\u7814\u7a76\u79ef\u7d2f\uff0c\u81f3\u4eca\u5c1a\u672a\u6709\u6709\u6548\u7684\u6cbb\u7597\u65b9\u6cd5\u6216\u9884\u9632\u63aa\u65bd\u3002\u5728\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u3001\u5e15\u91d1\u68ee\u75c5\u3001\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\uff08Lou Gehrig\u75c5\uff09\u53ca\u591a\u53d1\u6027\u786c\u5316\u75c7\u7b49\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u4e2d\uff0c\u7ebf\u7c92\u4f53\u529f\u80fd\u969c\u788d\u662f\u5176\u6838\u5fc3\u75c5\u7406\u7279\u5f81\u4e4b\u4e00\u3002<\/p>\n\n\n\n<p>\u7ebf\u7c92\u4f53\u89e3\u5076\u8054\u5242\u53ef\u4ee5\u5e2e\u52a9\u51cf\u5c11\u6c27\u5316\u5e94\u6fc0\u5e76\u9632\u6b62\u7ebf\u7c92\u4f53\u9499\u8d85\u8f7d\u3002\u7ed3\u5408\u53ef\u6539\u5584\u795e\u7ecf\u5143\u7ebf\u7c92\u4f53\u5065\u5eb7\u7684\u5176\u5b83\u673a\u5236\uff0c\u5176\u6709\u671b\u5728\u672a\u6765\u6210\u4e3a\u66f4\u4e3a\u6709\u6548\u7684\u6cbb\u7597\u9009\u62e9\u3002<\/p>\n\n\n<\/div>\n\n\n<\/div><\/div><\/div><div class=\"safezoneA\"><div class=\"site-content content2\"><article><div class=\"entry-content\">\n\n\n\n<h2 class=\"wp-block-heading\">\u5408\u4f5c\u4e0e\u4f19\u4f34\u5173\u7cfb<\/h2>\n\n\n\n<p>\u541b\u5723\u6cf0\u81f4\u529b\u4e8e\u901a\u8fc7\u5efa\u7acb\u5408\u4f5c\u4e0e\u4f19\u4f34\u5173\u7cfb\uff0c\u5c06\u521b\u65b0\u4e14\u5177\u6709\u53d8\u9769\u6027\u7684\u836f\u7269\u5e26\u7ed9\u5168\u7403\u60a3\u8005\u3002\u6211\u4eec\u79ef\u6781\u5bfb\u627e\u5fd7\u540c\u9053\u5408\u7684\u4f19\u4f34\uff0c\u5171\u540c\u5f00\u521b\u7a81\u7834\u6027\u6cbb\u7597\u65b9\u6848\uff0c\u5229\u7528\u6700\u524d\u6cbf\u7684\u7814\u7a76\u6210\u679c\u548c\u6280\u672f\u624b\u6bb5\u63a8\u52a8\u7814\u53d1\u6709\u6548\u7597\u6cd5\u3002\u6211\u4eec\u5c24\u5176\u5173\u6ce8\u4ee5\u4e0b\u9886\u57df\u7684\u5408\u4f5c\u673a\u4f1a\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u63a2\u7d22\u4e3b\u8981\u4e34\u5e8a\u5019\u9009\u836f\u7269HTD1801\u7684\u5176\u4ed6\u9002\u5e94\u75c7<\/li>\n\n\n\n<li>\u52a0\u5feb\u63a8\u8fdb\u65e9\u671f\u7814\u53d1\u9879\u76ee\u7684\u7814\u53d1\u8fdb\u7a0b\uff0c\u81f4\u529b\u4e8e\u89e3\u51b3\u80a5\u80d6\u548c\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u6cbb\u7597\u9700\u6c42<\/li>\n<\/ul>\n\n\n\n<p>\u5982\u6709\u5408\u4f5c\u610f\u5411\uff0c\u8bf7\u8054\u7cfb\u6211\u4eec\uff1a <a href=\"mailto:bd@hightidetx.com\" target=\"_blank\" rel=\"noreferrer noopener\">bd@hightidetx.com<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u541b\u5723\u6cf0\u7684\u65e9\u671f\u7814\u53d1\u5e03\u5c40\u4f53\u73b0\u4e86\u6211\u4eec\u81f4\u529b\u4e8e\u63a8\u52a8\u53d8\u9769\uff0c\u4ee5\u653b\u514b\u6162\u6027\u4ee3\u8c22\u75be\u75c5\u548c\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u51b3\u5fc3\u3002 \u9664\u4e86\u5df2\u5904\u4e8e\u4e34\u5e8a\u9636\u6bb5\u7684 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